Retreat Würzburg 2018

Program Young Investigor Retreat of the SPP 1782


21.03. and 22.03.2018 in Würzburg

Location:
Zentrum Operative Medizin (ZOM)
Seminarraum 2/3; EG
Oberdürrbacher Straße 6
97080 Würzburg

Wednesday, 21.03.2018


Part I: Presentation of data from the projects
10:00-10:15h Welcome
10.15-10:30h Desmoplakin bears tension when exposed to mechanical stress
Anna-Lena Cost; Max-Planck-Institut für Biochemie, Martinsried
10:30-10:45h Investigating Desmoplakin Disease Mutants with Force-Probe
Molecular Dynamics
Csaba Daday; Heidelberg Institute for Theoretical Studies
10:45-11:00h Coupling of polarity and mechanical signals at epidermal junctions
Martim Gomes; Iden Lab, CECAD
11:00-11:15h The role of desmosomal components in the intestine
Annika Groß; Medizinische Klinik III, Uniklinik Aachen
11:15-11:30h Role of JAM Family Adhesion Molecules in Epithelial Cells
Christian Hartmann
ZMBE Münster- Institut für med. Biochemie, AG Prof. Ebnet
11:45- 12:00 p120ctn is a mechanotransducer to promote E-Cadherin turnover and tissue viscoelasticity
Iyer K. Ventakesan, MPI-CBG
12:00- 12:15h Cell defect and layer integrity studies in Keratinocytes
Susanne Karsch
Institut für Physikalische Chemie, Universität Göttingen
12:15-12:30h Organ and Single Cell Morphological Analysis in the Zebrafish Lateral Line System".
David Kleinhans; Goethe Universität Frankfurt
12:40- 12:45h Open Discussion
12:45-14:00h Lunch Break
Part II: Presentation and discussion of techniques and collaborations
14:00-15:30 Hot topic AFM
14:00- 14:15 Atomic force microscopy- principle and basic steps of realization
Susanne Karsch
14:15- 14:30h What can we really measure with Atomic force microscopy?
Dave Ahrens
14:30- 15:15 Open Discussion on technical questions and collaborations
15:15- 15:30 Coffee break
15:30- 17:00h Hot topic cell imaging and microscopy
15:30- 15:45h Basic steps in live fluorescence microsopy
Marcin Moch
15:45- 16:00h Approaches for processing and analysing image data in the life
sciences
David Kleinhans
16:00- 17:00 Open Discussion on technical questions and collaborations
18:30 Uhr Get together and Dinner

Thursday; 22.03.2018

Part III: Presentation of data from the projects
09:30-9:45h Desmosome dependent keratin dynamics and organization
Marcin Moch; Institute of Molecular and Cellular Anatomy, University
Hospital RWTH Aachen
09:45-10:00h Regulation of plakophilin 3 by EGF signaling;
Karin Rietscher; MLU Halle-Wittenberg
10:00- 10:15h Dsg2 regulates intestinal epithelial cell adhesion and barrier function
via EGFR
Hanna Ungewiß; Uni München
10:15-10:30h Coordination of surfaces of two different tissues through E-Cadherin
spot junctions
Vanessa Weichselberger, Albert Ludwigs University of Freiburg
10:30-10:45h Mechano-dependent control of cell behavior in Drosophila embryo
Prachi Richa, Institute for Developmental Biochmestry, Universität
Göttingen
10:45-11:00h Semi-automated analysis of epithelial spheroid polarity in 3D culture
Birga Sötje; Medizinische Hochschule Hannover
11:00-11:15h Coffee break
Part IV: Presentation and discussion of techniques and collaborations
11:15-12:30 Hot topic 3D-cultures and organoid cultures
11:15- 11:30 How to generate intestinal organoids
Annika Groß
11:30- 11:45h Basic steps in 3D-Cell Culture
Christian Hartmann
11:45- 12:30 Open Discussion on technical questions and collaborations, final
discussion; Lunch/Snack

General information:

The meeting is open to all SPP members and associated groups and aims to provide a
discussion point for data and especially to intensify collaborations and elucidation of common
principles. The meeting is especially for the Ph-D students and the young scientists and is
thought offer a platform for discussion of their recent data.

The meeting of SPP1782 will take place from March 21st to 22nd at the Zentrum für Operative
Medizin (ZOM), Oberdürrbacherstraße 6, 97080 Würzburg.

Location: Würzburg

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