Young Scientist Meeting / Würzburg

Location:
Zentrum Operative Medizin (ZOM)
Seminarraum 2/3; EG
Oberdürrbacher Straße 6
97080 Würzburg


Monday, 18.11.2019

10:30-10:40 Welcome
10:40 – 11:00 Mark Skamrahl
Force Transmission in epithelial and collective migration
11:00-11:20 Robin Püllen (AG Merkel/Hoffmann)
Responses to mechanical strain in three-dimensional epidermal systems
11:20-11:40 Fan Jin (AG Gräter)
Molecular mechanisms of E-cadherin mediated mechano-sensing
11:40 – 12:00 Ana Diaz /Mitchell Han (AG del Campo)
2.5D Artificial microenvironments to study mechanochemical sensing at intercellular junctions
12:00 -12:20 Lukas Windgaße (AG Grasshoff)
Investigating mechanical loading at intercellular junctions
12:20-13:20 Lunch Break
13:20 – 13:40 AG Niessen (TBA)
13:40-14:00 Martim Gomes (AG Iden)
Coupling of polarity and mechanical signals at epidermal junctions
14:00-14:20 Marcin Moch,(AG Leube)
Actin and the keratin-desmosome scaffold
14:20-14:40 Lisa Müller (AG Hatzfeld)
Role of Plakophilin 3 in desmosome assembly and cell proliferation
14:40-15:00 Fanny Büchau (AG Magin)
Keratin-dependent regulation of desmosome composition and stability
15:00 -15:15 Coffee Break
15:15 – 15:35 Jing Wang (AG Dahmann)
Interplay between mechanical tension and cytoskeletal organization in cell seperation at compartment boundaries in Drosophila

Tuesday, 19.11.2019

9:00-9:20 Ann-Christin Groh (AG Krahn/Weide)
Pals1 as a signaling hub at polarized epithelial cells
9:20-9:40 Simona Lüttgenau (AG Krahn/Weide)
Loss of Pals1 enhances cell migration by promoting Arf6-dependent Rac1 activity in colorectal cancer cells
9:40 – 10:00 Lena Thiess (AG Breuhahn)
Connecting junctional proteins with Hippo/YAP pathway activity in hepatocellular carcinoma
10:00:-10:20 Ngo Anh Phuong (AG Lopez-Posadas)
Piezo mechanosensitivity receptor interplay with tight junction proteins for maintenance of epithelial cell number and integrity’
10:20-10:40 Nadine Klusmeier (AG Schnittler)
Ectopic VE-cadherin expression of breast carcinoma cells modulates endothelial barrier function differentiation-dependently during early steps of metastasis
10:40 – 11:00 Coffee Break
Presentation and discussion of techniques
11:00 – 11:15 Jing Wang
Fluorescence Recovery After Photobleaching(FRAP)- Experiment and Data Analysis
11:15 – 11:30 Lisa Müller (AG Hatzfeld)
Quantification of Immunostainings
11:30 – 11:45 Anna-Lena Cost (AG Grasshoff)
FLIM to meause FRET
11:45-12:00 Final discussion
Lunch/Snack

General information:

The meeting is open to all SPP members and associated groups and aims to provide a discussion point for data and especially to intensify collaborations and elucidation of common principles. The meeting is especially for the Ph-D students and the young scientists and is thought offer a platform for discussion of their recent data.

Venue of the meeting:

The meeting of SPP1782 will take place at the Zentrum für Operative Medizin (ZOM), Oberdürrbacherstraße 6, 97080 Würzburg.
The venue can be reached from the city with a 30-35min walk or by Tram 1 and 5 (Direction Grombühl/Universitätskliniken; exit Robert Koch Straße Universitätsklinikum Bereich B; the way to ZOM will be signed out)

Location: Würzburg

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